USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

USC-OGP 2-DE database  Search by                Maps             Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal World-2DPAGE Repository Exclude local DBs has only effect if a remote interface is selected

Searching in 'USC-OGP 2-DE database' for entry matching: MYL6_HUMAN USC-OGP 2-DE database:  MYL6_HUMAN MYL6_HUMAN General information about the entry View entry in simple text format Entry name MYL6_HUMAN Primary accession number P60660 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Myosin light polypeptide 6; AltName: Full=17 kDa myosin light chain; Short=LC17; AltName: Full=Myosin light chain 3; Short=MLC-3; AltName: Full=Myosin light chain alkali 3; Short=Myosin light chain A3; AltName: Full=Smooth muscle and nonmuscle myosin light chain alkali 6;. Gene name Name=MYL6 Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein UVEAL_MELANOMA_3-10 {UVEAL MELANOMA 3-10} Homo sapiens (Human)   map experimental info   UVEAL_MELANOMA_3-10 MAP LOCATIONS: SPOT OGP-1284: pI=5.84; Mw=25790 SPOT OGP-1315: pI=4.59; Mw=20102 SPOT OGP-1329: pI=4.39; Mw=16914 Cross-references UniProtKB/Swiss-Prot P60660; MYL6_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name MYL6_HUMAN Primary accession number P60660 Secondary accession number(s) P16475 P24572 P24573 Q12790 Q561V9 Q6IAZ0 Q6IPY5 Sequence was last modified on  January 23, 2007 (version 2) Annotations were last modified on  March 15, 2017 (version 140) Name and origin of the protein Description RecName: Full=Myosin light polypeptide 6; AltName: Full=17 kDa myosin light chain; Short=LC17; AltName: Full=Myosin light chain 3; Short=MLC-3; AltName: Full=Myosin light chain alkali 3; Short=Myosin light chain A3; AltName: Full=Smooth muscle and nonmuscle myosin light chain alkali 6; Gene name Name=MYL6 Encoded on Name=MYL6 Keywords Acetylation; Alternative splicing; Complete proteome; Direct protein sequencing; Motor protein; Muscle protein; Myosin; Phosphoprotein; Polymorphism; Reference proteome; Repeat. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL M22918; AAA36347.1; -; mRNA EMBL M22919; AAA59892.1; -; Genomic_DNA EMBL M22919; AAA59893.1; -; Genomic_DNA EMBL M22920; AAA36348.1; -; mRNA EMBL M31212; AAA59853.1; -; mRNA EMBL U02629; AAA20643.1; -; mRNA EMBL AB046613; BAB62402.1; -; mRNA EMBL CR457014; CAG33295.1; -; mRNA EMBL BC006781; AAH06781.2; -; mRNA EMBL BC017455; AAH17455.1; -; mRNA EMBL BC071661; AAH71661.1; -; mRNA EMBL BC093066; AAH93066.1; -; mRNA CCDS CCDS31834.1; -. [P60660-2]; . CCDS CCDS8906.1; -; . PIR A33709; MOHU6N; . PIR A49620; MOHU6E; . PIR B33709; MOHU6M; . RefSeq NP_066299.2; NM_021019.4. [P60660-1]; . RefSeq NP_524147.2; NM_079423.3. [P60660-2]; . UniGene Hs.632717; -; . ProteinModelPortal P60660; -; . SMR P60660; -; . BioGrid 110721; 66; . IntAct P60660; 43; . MINT MINT-1131667; -; . STRING 9606.ENSP00000446714; -; . iPTMnet P60660; -; . PhosphoSitePlus P60660; -; . SwissPalm P60660; -; . BioMuta MYL6; -; . DMDM 47606436; -; . DOSAC-COBS-2DPAGE P60660; -; . SWISS-2DPAGE P60660; -; . EPD P60660; -; . MaxQB P60660; -; . PaxDb P60660; -; . PeptideAtlas P60660; -; . PRIDE P60660; -; . TopDownProteomics P60660-1; -. [P60660-1]; . TopDownProteomics P60660-2; -. [P60660-2]; . DNASU 4637; -; . Ensembl ENST00000547649; ENSP00000446714; ENSG00000092841. [P60660-2]; . Ensembl ENST00000548293; ENSP00000448101; ENSG00000092841. [P60660-1]; . Ensembl ENST00000550697; ENSP00000446955; ENSG00000092841. [P60660-1]; . GeneID 4637; -; . KEGG hsa:4637; -; . UCSC uc001sjw.3; human; . CTD 4637; -; . GeneCards MYL6; -; . HGNC HGNC:7587; MYL6; . HPA HPA046859; -; . HPA HPA063034; -; . MIM 609931; gene; . neXtProt NX_P60660; -; . OpenTargets ENSG00000092841; -; . PharmGKB PA31384; -; . eggNOG KOG0030; Eukaryota; . eggNOG COG5126; LUCA; . GeneTree ENSGT00590000082921; -; . HOVERGEN HBG012180; -; . InParanoid P60660; -; . KO K12751; -; . PhylomeDB P60660; -; . TreeFam TF351553; -; . Reactome R-HSA-3928663; EPHA-mediated growth cone collapse; . Reactome R-HSA-416572; Sema4D induced cell migration and growth-cone collapse; . Reactome R-HSA-445355; Smooth Muscle Contraction; . Reactome R-HSA-5625740; RHO GTPases activate PKNs; . Reactome R-HSA-5625900; RHO GTPases activate CIT; . Reactome R-HSA-5627117; RHO GTPases Activate ROCKs; . Reactome R-HSA-5627123; RHO GTPases activate PAKs; . ChiTaRS MYL6; human; . GeneWiki MYL6; -; . GenomeRNAi 4637; -; . PRO PR:P60660; -; . Proteomes UP000005640; Chromosome 12; . Bgee ENSG00000092841; -; . CleanEx HS_MYL6; -; . ExpressionAtlas P60660; baseline and differential; . Genevisible P60660; HS; . GO GO:0005903; C:brush border; IDA:UniProtKB; . GO GO:0005829; C:cytosol; TAS:Reactome; . GO GO:0070062; C:extracellular exosome; IDA:UniProtKB; . GO GO:0031012; C:extracellular matrix; IDA:BHF-UCL; . GO GO:0016020; C:membrane; IDA:UniProtKB; . GO GO:0016459; C:myosin complex; TAS:HGNC; . GO GO:0016461; C:unconventional myosin complex; TAS:BHF-UCL; . GO GO:0031982; C:vesicle; IDA:UniProtKB; . GO GO:0030898; F:actin-dependent ATPase activity; ISS:HGNC; . GO GO:0005509; F:calcium ion binding; IEA:InterPro; . GO GO:0003774; F:motor activity; TAS:HGNC; . GO GO:0008307; F:structural constituent of muscle; IDA:HGNC; . GO GO:0006936; P:muscle contraction; TAS:HGNC; . GO GO:0030049; P:muscle filament sliding; TAS:HGNC; . GO GO:0007519; P:skeletal muscle tissue development; TAS:UniProtKB; . CDD cd00051; EFh; 1; . Gene3D 1.10.238.10; -; 2; . InterPro IPR011992; EF-hand-dom_pair; . InterPro IPR002048; EF_hand_dom; . Pfam PF13405; EF-hand_6; 1; . SMART SM00054; EFh; 2; . SUPFAM SSF47473; SSF47473; 1; . PROSITE PS50222; EF_HAND_2; 2; .

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• The World-2DPAGE Constellation - Entry point to the world-wide 2-DPAGE resources.
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• SWISS-2DPAGE - The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
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